Characterizing complex structural variation in germline and somatic genomes
نویسندگان
چکیده
منابع مشابه
Characterizing complex structural variation in germline and somatic genomes.
Genome structural variation (SV) is a major source of genetic diversity in mammals and a hallmark of cancer. Although SV is typically defined by its canonical forms (duplication, deletion, insertion, inversion and translocation), recent breakpoint mapping studies have revealed a surprising number of 'complex' variants that evade simple classification. Complex SVs are defined by clustered breakp...
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ژورنال
عنوان ژورنال: Trends in Genetics
سال: 2012
ISSN: 0168-9525
DOI: 10.1016/j.tig.2011.10.002